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OPA-based assays are more sensitive but unstable, which affects accuracy and precision [86], whereas DTNB-based assays allow for determination of biothiols in the presence of other amino acids and polyphenolic antioxidants but are less sensitive [82]

The principal role of the interdisciplinary team is to provide integrated case management for the child and to assure the quality and continuity of care and long-term followup

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